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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c05df3c5f230f94e78fe1ab7c8bdb851710f56de5a915c3929f86237243abd' 
  AND token = 'CD3nVVWR83fh9nGV/OMCwMgVcRMD9ynLWpGgm2TV7/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}