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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be2a0fa45af375d6080f5a4f16d322ef8b3838c5180ef4b19922f5f42f8ef03' 
  AND token = 'MB873s+HtH0CZbxkcenL3qEuOzDTXEx4R/O2Qzqarws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}