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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b765261250f229a300e071a25c80990bc828358020939b78b4df6dc2932eac' 
  AND token = 'XZvfwVt+51EFIRljueRa/SW76exqI5Wfk+M9vir3Yho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}