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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195d21dfc66c72a5d687d8020572b73f8836ed5d12fb5da6ffee72b977c2d35a' 
  AND token = 'NtRrL0UBpxgrObSlTQhKxhvZfFYdilx/cSk7XQYKPwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}