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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52650add5273841c01f1cc44368020486c2d15d58d93597320b9220454651ba' 
  AND token = 'YgH6umNghD2akIgoDxdvEwfvS5v1m3fwCjPRj2MqixM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}