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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a8e339854961a6ff7e2393cb0345d1c01ad6a3cb77f1261fbfd9fccd454cc9a' 
  AND token = 'NYIFj69YKsU6ZdW5TsjINookBQalkFWBngdSkPTxSPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}