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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7bcfa7b38b6b97a35ccee53f12826c03c8bbea52efacff13d6290ad8b6e9222' 
  AND token = 'dlvHtIY9KNoKQsl2uAcyhdpxUZD0D8VCf9S7kIdkDsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}