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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64909e044630d185f67dddb8c664210234f75586d966604026aca16daef8ed8d' 
  AND token = '6+mtExaNK+YsqXRWAbVgWj9KdNi3US3oJuX2SGif1jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}