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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72caf87befe8547880ecd65f0722aa573a047291c6e6d92082b0bb15d91c5a6d' 
  AND token = '9Qap8vETCsFf1vVwNl29EOgKT5qYSaGGQ9GYXSoKteQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}