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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb187dac9610ed47e3e46eee695f75f91c13a9c85ed9cd1ad080673859774445' 
  AND token = 'fKqkyrbI1HWjKrIlshyi4jBOaxnIDr7OX7/imym227k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}