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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fb87c42d78f5f8f0e764282f7a7c3ceabe6381dedb8254b62253e6eb6f21874' 
  AND token = 'z9aCDWbm9owIAMPQaUVa4eZJc72TPrx1S1kr22B/tDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}