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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa2bef894a7be3881f0a826682db76cbeafce5a2899ca2ab142647d72d4f1e12' 
  AND token = 'Egvn7S9Pjq1u2N7mZ9xLs33DY0MuRHxORq/KsrOCGDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}