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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa9fbc6f634f83ace4f26c9c39ed5094f8e70e7de77f217724587d3c5274339a' 
  AND token = 'RXXcEi3x6F7kbMPkZLDSy0VVRM/EuZATAu1BCDA5AY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}