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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3d739f4a91f35d0bc98b5b109588a388ce1688397463d6b395cc0ec18db6db' 
  AND token = 'NrpoI84gZoBcnv9PKXygO+24UwtuHh312KyLoUpFDZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}