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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5310c7d5d6d51e48ebdd5d781ddb1f4eee49a15be2a17c3333dd536cd728b3c7' 
  AND token = 'PIhLYOK77sJyryYwCyXrzqx40anqX2XUt9E+LZl0TW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}