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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b78ed273bc8002d8a5f509b25e1a2749bb778b615e5bf1e136249317aad5c139' 
  AND token = 'rPc3G9EF9LnmfGL7S6Gc0soBzX+gbytsKBdyLQlMpio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}