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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6573f77f9a4c2a3e5b626fed37572ab645ab226b469d1e3074130f0f8cec73' 
  AND token = 'fFUkqU2D0DScb5S6aWqfg3xRpmDXqNxY5Tf2meLVWII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}