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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d845ae9cfc6999494c277d05ff39d180f889ac720b95e807a9670f958625f75' 
  AND token = '2a9Kb/j21hMz0pS0L6/evuppUEq6/6nQmGmMuFOy/z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}