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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e4616e423549e8297daa54ea69d1e4a1d0ad06a75b9caf4398a28e51f56464' 
  AND token = 'DuvXe3VV4y+d1R1rdflbtd25zzWrFqRFEh0tHxb8zgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}