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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5234d21fb44d14c72097b58f9123b09918011ab327ef368f34d9650dc4c065a3' 
  AND token = 'rHDgAn+sjMK5t5QkHaizkYbGHpYYpFlUDe9idZ/557I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}