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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c150c856abd4c5bf83392ab5e102cf0279fd09e9141a3c9aff47920f40f498' 
  AND token = 'lPhfsPGBZMnI40YPwgQo/aegXza7B/78aI5G74bsA9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}