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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c674725d6be5674ab538b93e7d416740efc9b0a1c79a1db5671c66eebb4274a1' 
  AND token = 'AcHAi0n8RojCqWrn0vH+qIcKMsJX2yBy3KW75e3VnJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}