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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a4e35a0b797a80a6d396d0085bb3e0dff24af8820e3aa393c961a63a9666a5e' 
  AND token = 'SUJNTunDUZ/5YBvySs/WjSXOO+mANrBkQeVIKgOM6GQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}