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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1d3c01f84cb44a3876fa0a865ca2e2be9df956de632e2f6bdbb355a9011469d' 
  AND token = 'yoY420T4CPhaXN3flukfktTyKDsY71rqMgwAM5+KMTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}