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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bb4f06cc49dcfe892b20eb0dc22d61c2f7a7b526f44244b2d485f68a7451e8f' 
  AND token = 'RDt0Ttsz/8bNKVC7Zs8K7zspnQxYLGXg/WZ5vHkKAic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}