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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab52950fc5c4a19686991fa1de5b243b56cc3d3f970df26cc55a0b0b82ba64b4' 
  AND token = '8LTqm9geFg/QsvZEwo14Pd9fcE9dGMyCVxzVvnQ12FM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}