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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68591ab9fc465adbaab9a55901fd01da1e9be083cdc08c4dd6b7844c0890cc20' 
  AND token = 'UOymlpa8/lKfpRMprVFjNIf2B0poF01sizOm9h5KuLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}