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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e5296f829ef9e5d31ff5e763f4e60113e62d22876ed10a75ad003d5f4246ad' 
  AND token = '0+Hqf25Ufyn/HXDeTL/lI+TBbJf5DkoTOBddUFZNrBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}