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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7f9d662d29a1009068c3ec8fd068a8a3402e3d54ebaff601b0cf338d7a2a068' 
  AND token = 'mQPiTByTJAQchYVn9+zpc0OWr4CAMTm0uA/gl1ObI0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}