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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a37f43e00df39200cf51ce45f282bac8ad51868d09e62755532a40e5f4a8f215' 
  AND token = 'ka1iLz9UOXq3gMhRbxtJMYyEtancAt3HWmVjgGS+8zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}