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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4535e330f1d0b90b784a5519385bb79f6454bdb8220244af1654e8d2c7ca3a75' 
  AND token = 'rlUVtUuBF4NdQ/NhrRZOHQDEp8fCzOxbuEQoqKKT0d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}