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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb50a4da7c7101e6758b0a755195484d3d23739b95d588b3efd8d4a4527e0578' 
  AND token = '6+GVm16oE7OjQrRkuX1E7Pbnx3DlDniWurXFiKOFcqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}