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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65c5a1e86e04e5e46655d45554a0252ec897173f8dfaf7a6b8218c9514adb8e' 
  AND token = 'W2HcAE+l6UdvQ7oLLdo7E0pkPqnkTt9QPmg8CFyWobo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}