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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f1d09130f914d8aee12ddbe2bd19e05100e6d55b05c5b0352cc6bb78e8abb15' 
  AND token = '5ZatQp9cWLPC2CdJoVBTnqTSIUKFFOw8tgBrAIy/1Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}