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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10355d022acf2342e26c95501d26589cfe8e264ad396a90a5a02e952f4f76d8c' 
  AND token = 'FJL4lBjkTqq7+FNkUOBG1vA7wGFAG399edZNqlNgHqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}