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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0382fad6363804bce0dd9c99700ff11a7b7d86535466d07f3d0c3b83e830616' 
  AND token = '+TyglYFb4prVStCUjLRJfEMn4RkBEzjRdJzdxY/Jdq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}