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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '307a624d246dc7fdb80fe1cb8bf07557b5640aa67980c605cc75768cbb1caadc' 
  AND token = 'L1AFxnxOi4C9ZCmlUNYuUo5H/9aLtBXOAiETecTbd7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}