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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e44ccb05d6e2364f68cf37646cfb3d4119c2f43d72309b8a750d209de83fb5' 
  AND token = 'YNltc/JedOzUEyKOxKZbvwD7R9MUmc2ZIjXC9Wzsf00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}