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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a37c715f684ae750a7c70ddce27c692e2fe4c2ddce2876284cd27b5cfa44b379' 
  AND token = 'HItss0UwKL/cNBf2B/WdxRNPE/gauGPcJYcBNtRLj7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}