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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b0b7007e1d1484dba9fb9db3944ba417c15e5e56fcdce6b714b6c1ca02aa4f' 
  AND token = '3RRIee8HuDuelG6IhI3xt40BlOCMj3yNIcCq2I/47fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}