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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c21a3b9d47d46bf75be5564d0e3c3a283ef0da02473c77d18cdd215ddb788f4' 
  AND token = '3hthVyFAr1z7w3XeFQn0JsDHXb9ysmb8UhX5XeZ1JH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}