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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e224bb952c9ca1fac5ae4a91da5b731014af6eddbf2d1b2b15e41c045a6fea0a' 
  AND token = 'pJFDGbZetDL9GH/LGEQVN1fLyRvRQVJrEIA3t6yTnPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}