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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f072d24a4ca62f8d42710dc4b79ee7e72364cd02ff3c7343e2249b25c8c62e' 
  AND token = 'HqfEq977NKbtWhjPy6Gp/fGUNxa5SzIL0hyOo4JXtoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}