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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '611e4a147fc45b5453ba56b2b4bf9302bbc5e1274f5a8665ab7a58519e13026a' 
  AND token = 'cHO/Nne7YBAXquULT4XgyG7jIVG46AGJM3MyLslD9RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}