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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5757f0d6beb1407b1ac07c05e14a9890c5a7a884ab1e8e5c09d121b0d533c1e7' 
  AND token = 'XysI9rD0WHdh/Jx6DH1jdfJyKQz3PqSg+fAVwBDUd0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}