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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c887c710e740089794e0ac13baf2c87db06b955a4076be6a4c428cf6e73135e2' 
  AND token = 'Il0mRkE66DU2ePgDC9Jy+oCrAA4SWzbMYvmL7wM7cfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}