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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d463b5359cef8997cdf075b4de5232ee7cdfe0dec42cfc1013003ec750f491b' 
  AND token = '9jmLTBuWPS3U/CB2RdX/BmNkW1cdU6ogvchZrnzVA9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}