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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d52ca527e6a91b6c701064a3e21bf9f2dacaa2d1052694f2edc57eddaaabc26' 
  AND token = 'ZeEwCDgGen+KEk0Q9GAd++6w+xkU0o28Bc1ojCgvVWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}