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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02641c1c81f1e58f4646acefbce30640386e1db2cb2129954170473b80581d62' 
  AND token = 'o607ZRk3ipEmRC1LTCzonD55LR2vstQI28pNxzz2WEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}