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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e86fc2f4fb96ee369187ede09b6974a83465baa65356a0234ec88134d9bde3ee' 
  AND token = 'B1wMoxm2rcvOSuOLTDf6Iy9xwcLJIdD+uAoArOSL8ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}